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Pharmacokinetic behavior and tissue distribution of verapamil and its enantiomers in rats by HPLC

โœ Scribed by Langchong He; Sicen Wang

Book ID
105672639
Publisher
Springer
Year
2003
Tongue
English
Weight
500 KB
Volume
26
Category
Article
ISSN
0253-6269

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PHARMACOKINETICS OF THE ENANTIOMERS OF V
PHARMACOKINETICS OF THE ENANTIOMERS OF VERAPAMIL AFTER INTRAVENOUS AND ORAL ADMINISTRATION OF RACEMIC VERAPAMIL IN A RAT MODEL
โœ M. MASOOD BHATTI; ROBERT T. FOSTER ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 111 KB ๐Ÿ‘ 2 views

Verapamil is a chiral calcium channel blocking drug which is useful clinically as the racemate in treating hypertension and arrhythmia. The published pharmacokinetic data for verapamil enantiomers in the rat model are limited. Utilizing a stereospeciยฎc highperformance liquid chromatographic (HPLC) a