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Pharmacokinetic and clinical implications of quinidine protein binding

✍ Scribed by Elaine Woo; David J. Greenblatt

Publisher
John Wiley and Sons
Year
1979
Tongue
English
Weight
599 KB
Volume
68
Category
Article
ISSN
0022-3549

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Significance of protein binding in pharm
Significance of protein binding in pharmacokinetics and pharmacodynamics
✍ Stephan Schmidt; Daniel Gonzalez; Hartmut Derendorf πŸ“‚ Article πŸ“… 2010 πŸ› John Wiley and Sons 🌐 English βš– 243 KB

The significance of plasma protein binding on drug efficacy and, subsequently, the clinical relevance of changes in protein binding has been controversially discussed for decades. The uncertainty concerning the impact of plasma protein binding on a drug's pharmacological activity is, in part, relate