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Pharmacodynamics and pharmacokinetics of the methyl ester of 15-deoxy-16-hydroxy-16-vinylprostaglandin E2

✍ Scribed by Vijay K. Batra; John A. Morrison; Donna B. Cosulich; William Dougherty; Nancy Perkinson; Michael Kohlbrenner; Andrew Barr; Avraham Yacobi

Publisher
John Wiley and Sons
Year
1985
Tongue
English
Weight
220 KB
Volume
74
Category
Article
ISSN
0022-3549

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Syntheses of 3H- and 2H-labeled (16S)-15
Syntheses of 3H- and 2H-labeled (16S)-15-deoxy-16-hydroxy-16-methyl-5-thiaprostaglandin E1 methyl esters
✍ Satoshi Sugiura; Toshio Tanaka; Kiyoshi Bannai; Seizi Kurozumi 📂 Article 📅 1991 🏛 John Wiley and Sons 🌐 French ⚖ 498 KB

## Abstract The syntheses of [7‐^2^H]‐, [7‐^3^H]‐, and [2,2,3,3,4,4‐^2^H~6~]‐(16__S__)‐15‐deoxy‐16‐ hydroxy‐16‐methyl‐5‐thiaprostaglandin E~1~ methyl ester (2, 3, and 4) are described. Both 7‐labeled compounds, 2 and 3, were prepared from the Δ^7^‐precursor (11) by treatment with __in‐situ__ genera