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Pharmacodynamic measurement of percutaneous penetration enhancement in vivo

✍ Scribed by Kamaljit S. Ryatt; John M. Stevenson; Howard I. Maibach; Richard H. Guy


Publisher
John Wiley and Sons
Year
1986
Tongue
English
Weight
441 KB
Volume
75
Category
Article
ISSN
0022-3549

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## Abstract ## Background and Objectives (Pre)cancerous skin lesions accumulate more protoporphyrin IX (PpIX) upon topical application of 5‐aminolevulinic acid (ALA) than the surrounding normal skin. This might be the result of a higher percutaneous penetration of ALA into (pre)cancerous skin. ##