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Pharmacodynamic markers for histone deacetylase inhibitor development

✍ Scribed by Thorsten Heinzel; Oliver H. Krämer

Book ID
119225522
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
908 KB
Volume
4
Category
Article
ISSN
1740-6765

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## Abstract Histone deacetylases (HDACs) are a family of enzymes that have been of interest in drug discovery for more than 30 years. Inhibitors of HDACs are potential therapeutics for various diseases, such as neurodegenerative diseases, inflammation, viral infection, and especially cancer. Most H