## Abstract Histone deacetylases (HDACs) are a family of enzymes that have been of interest in drug discovery for more than 30 years. Inhibitors of HDACs are potential therapeutics for various diseases, such as neurodegenerative diseases, inflammation, viral infection, and especially cancer. Most H
ChemInform Abstract: Strategies in Developing Promising Histone Deacetylase Inhibitors
β Scribed by Lei Zhang; Hao Fang; Wenfang Xu
- Publisher
- John Wiley and Sons
- Year
- 2010
- Weight
- 15 KB
- Volume
- 41
- Category
- Article
- ISSN
- 0931-7597
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## Abstract A library of small molecule inhibitors of histone deacetylase is prepared by coupling of macrocyclic aldehydes such as (VII) with bifunctional hydrazide reagents.
## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a βFull Textβ option. The original article is trackable v
## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 200 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a βFull Textβ option. The original article is trackable v