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Pharmacodynamic analysis of steroid 5α-reductase inhibitory actions of Z-350 in rat prostate

✍ Scribed by Shigeru Furuta; Youich Fukuda; Tohru Sugimoto; Haruka Miyahara; Emiko Kamada; Hiroshi Sano; Yoshihisa Fukuta; Mineo Takei; Tadashi Kurimoto

Book ID
114014141
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
119 KB
Volume
426
Category
Article
ISSN
0014-2999

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## Abstract Prolactin (PRL) is implicated in prostate growth and in the development and regulation of benign prostatic hypertrophy (BPH) and prostate cancer (PCa). PRL may exert its effects on prostate in synergism with androgens. The most active androgen in the prostate is the 5α‐dihydrotestostero