β Scribed by Ronald S. Oosting Ph.D. (auth.), Daan J. A. Crommelin, Robert D. Sindelar, Bernd Meibohm (eds.)
No coin nor oath required. For personal study only.
This introductory text explains both the basic science and the applications of biotechnology-derived pharmaceuticals, with special emphasis on their clinical use. It serves as a complete one-stop source for undergraduate/graduate pharmacists, pharmaceutical science students, and for those in the pharmaceutical industry The Fourth Edition will completely update the previous edition, and will also include additional coverage on the newer approaches such as oligonucleotides, siRNA, gene therapy and nanotech.
Front Matter....Pages i-xxi
Molecular Biotechnology: From DNA Sequence to Therapeutic Protein....Pages 1-18
Biophysical and Biochemical Analysis of Recombinant Proteins....Pages 19-45
Production and Purification of Recombinant Proteins....Pages 47-67
Formulation of Biotech Products, Including Biopharmaceutical Considerations....Pages 69-99
Pharmacokinetics and Pharmacodynamics of Peptide and Protein Therapeutics....Pages 101-132
Immunogenicity of Therapeutic Proteins....Pages 133-141
Monoclonal Antibodies: From Structure to Therapeutic Application....Pages 143-178
Genomics, Other βOmicβ Technologies, Personalized Medicine, and Additional Biotechnology-Related Techniques....Pages 179-221
Dispensing Biotechnology Products: Handling, Professional Education, and Product Information....Pages 223-235
Economic Considerations in Medical Biotechnology....Pages 237-245
Regulatory Framework for Biosimilars....Pages 247-254
Insulin....Pages 255-275
Follicle-Stimulating Hormone....Pages 277-283
Human Growth Hormone....Pages 285-298
Recombinant Coagulation Factors and Thrombolytic Agents....Pages 299-320
Recombinant Human Deoxyribonuclease I....Pages 321-336
Monoclonal Antibodies in Cancer....Pages 337-359
Hematopoietic Growth Factors: Focus on Erythropoiesis-Stimulating Agents....Pages 361-374
Monoclonal Antibodies in Solid Organ Transplantation....Pages 375-391
Monoclonal Antibodies and Antibody-Based Biotherapeutics in Inflammatory Diseases....Pages 393-412
Interferons and Interleukins....Pages 413-437
Vaccines....Pages 439-457
Oligonucleotides....Pages 459-475
Gene Therapy....Pages 477-507
Stem Cell Technology....Pages 509-524
Back Matter....Pages 525-544
Pharmaceutical Sciences/Technology; Biomedicine general
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<p><p>This introductory text explains both the basic science and the applications of biotechnology-derived pharmaceuticals, with special emphasis on their clinical use. It serves as a complete one-stop source for undergraduate/graduate pharmacists, pharmaceutical science students, and for those in t
This introductory text explains both the basic science and the applications of biotechnology-derived pharmaceuticals, with special emphasis on their clinical use. It serves as a complete one-stop source for undergraduate/graduate pharmacists, pharmaceutical science students, and for those in the pha
This introductory text explains both the basic science and the applications of biotechnology-derived pharmaceuticals, with special emphasis on their clinical use. It serves as a complete one-stop source for undergraduate/graduate pharmacists, pharmaceutical science students, and for those in the pha
Completely revised text that reflects to emergent trends and cutting-edge advances in pharmaceutical biotechnology, this Third Edition provides a well-balanced framework for understanding every major aspect of pharmaceutical biotechnology, including drug development, production, dosage forms, admini