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Phagocytosis and the sialic acid of the surface of polymorphonuclear leukocytes

✍ Scribed by John Noseworthy Jr.; Helen Korchak; Manfred L. Karnovsky

Publisher
John Wiley and Sons
Year
1972
Tongue
English
Weight
533 KB
Volume
79
Category
Article
ISSN
0021-9541

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✦ Synopsis

Treatment of polymorphonuclear leukocytes with sialidase releases about one-half of the total sialic acid of the cells. Such treatment af- fects neither phagocytic ingestion nor glycolysis. These results are in contrast to earlier data in the literature that indicate suppression of both functions mentioned upon desialation of these cells. The presence of an inhibitor of glycolysis that contaminated the crude enzyme previously used is suggested.

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