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Phagocytic microglia release cytokines and cytotoxins that regulate the survival of astrocytes and neurons in culture

✍ Scribed by Giulian, Dana; Li, Jun; Leara, Beth; Keenen, Charles

Book ID
125463104
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
703 KB
Volume
25
Category
Article
ISSN
0197-0186

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## Abstract Astrocytes play a key role regulating aspects of inflammation in the central nervous system (CNS). Several enzymes, such as the inducible nitric oxide synthase (iNOS) or the cyclooxygenase‐2 (COX‐2), along with different inflammatory mediators such as the free radical nitric oxide (NO)