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Lipopolysaccharide differentially regulates the production of matrix metalloproteinases by astrocytes and microglia in mixed or purified cell cultures

โœ Scribed by J. Lestage; N. Chauvet; D. Verrier; K. Palin; R. Dantzer


Book ID
117337798
Publisher
Elsevier Science
Year
1998
Tongue
English
Weight
138 KB
Volume
90
Category
Article
ISSN
0165-5728

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## Abstract Matrix metalloproteinases (MMPs) degrade the extracellular matrix and are implicated in the pathogenesis of several neurological diseases. Secreted in proforms, the MMPs require activation. Tissue inhibitors of matrix metalloproteinases (TIMPs) regulate the activity of MMPs. We investig