๐”– Bobbio Scriptorium
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Phagocytic leukocytes and reactive oxygen species

โœ Scribed by John M. Robinson


Publisher
Springer
Year
2009
Tongue
English
Weight
237 KB
Volume
131
Category
Article
ISSN
1432-119X

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## Abstract Leukocyte oxidative function was investigated in a more physiological milieu than currently used in the chemiluminescence (CL) technique. Heparinized blood was mixed with 6% dextranโ€T70 (9:1) and the leukocyteโ€rich plasma obtained without centrifugation was used for the CL experiments (

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Non-enzymatic glycosylation (NEG) of collagen has been previously shown to signiยฎcantly inยฏuence the reactive oxygen metabolism (ROM) of phagocytic cells in healthy subjects. Considering the role of NEG in the pathophysiology of diabetes, we have further analysed the oxidative metabolism of polymorp