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Ph1-positive CML in a 13;14 translocation carrier

✍ Scribed by Kohno, Sei-Ichi ;Sandberg, Avery A.


Publisher
John Wiley and Sons
Year
1978
Tongue
English
Weight
209 KB
Volume
5
Category
Article
ISSN
0098-1532

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✦ Synopsis


A 63-year-old woman with Ph1-positive CML and a constitutional 13;14 Robertsonian translocation is described. The rarity of this cytogenetic combination and the significance of the D/D translocation in the genesis of the Ph1 and other chromosome anomalies in myeloproliferative disorders is briefly discussed. It is concluded that the occurrence of the two cytogenetic anomalies and the clinical states is coincidental.


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