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pH-sensitive drug delivery system using OW emulsion

✍ Scribed by Soon Hong Yuk; Sun Hang Cho; Hai Bang Lee


Book ID
113275920
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
417 KB
Volume
37
Category
Article
ISSN
0168-3659

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## Abstract A novel pH‐sensitive nanoparticle drug delivery system for doxorubicin (DOX) is prepared. Pullulan, a natural biocompatible polysaccharide, was partly carboxymethylized; hydrazine hydrate was condensed with the carboxyl groups forming hydrazide. The hydrazide was coupled with DOX throug