Ph-negative chronic myelocytic leukemia with a complex translocation involving chromosomes 7 and 11
β Scribed by Toshio Takeda; Kenji Ikebuchi; Yuuji Zaike; Mayumi Mori; Kazuma Ohyashiki; Tatsuro Ikeuchi
- Book ID
- 119103172
- Publisher
- Elsevier Science
- Year
- 1986
- Tongue
- English
- Weight
- 369 KB
- Volume
- 21
- Category
- Article
- ISSN
- 0165-4608
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A Ph1 chromosome-negative chronic myelogenous leukemia (CML) with t(7;11)(p15;p15) in a 6-year-old girl is reported. Three cases of 7;11 translocation have been reported so far. The patients concerned were between 37 and 72 years of age; 2 of them had CML and the other had acute myelomonocytic leuke
We report on a 4-year-old boy with typical frontonasal dysostosis and an apparently balanced de novo translocation involving chromosomes 3, 7, and 11, and four breakpoints. The karyotype was 46,XY,t(7;3)(3;11) (7pter--+7q21.3:3q27-+3qter;3pter+3q23::11q21 -,rllqter;llpter+llq21::3q23--+3q2~.7q21.3-+
A 46-year-old man with chronic myelocytic leukemia had a new variant translocation between chromosome 22 and chromosome 7 in bone marrow cells. No involvement of chromosome 9 was seen. The patient entered blastic transformation within half a year, by which time he had acquired an isochromosome 17 in