𝔖 Bobbio Scriptorium
✦   LIBER   ✦

pH dependent cycloaromatization of enediyne model compounds via enyne-allene intermediates

✍ Scribed by Yoshimitsu Naoe; Junya Kikuishi; Katsuya Ishigaki; Hiromi Iitsuka; Hisao Nemoto; Masayuki Shibuya

Publisher
Elsevier Science
Year
1995
Tongue
French
Weight
242 KB
Volume
36
Category
Article
ISSN
0040-4039

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Synthesis of enediyne model compounds pr
Synthesis of enediyne model compounds producing toluene diradicals possessing a highly radical character via enyne–allene intermediates
✍ Ichiro Suzuki; Masakazu Wakayama; Akira Shigenaga; Hisao Nemoto; Masayuki Shibuy πŸ“‚ Article πŸ“… 2000 πŸ› Elsevier Science 🌐 French βš– 67 KB

Development of enediyne model compounds that produce dehydrotoluene diradicals under acidic media is described. The ionic character of the diradicals is shown to be avoided by the electron-withdrawing groups in the molecules both in benzene and MeOH.

Cycloaromatization of a 10-membered ened
Cycloaromatization of a 10-membered enediyne derivative via an allenic sulfone intermediate and its DNA cleaving activity
✍ Yasuhiro Sakai; Yuri Bando; Kozo Shishido; Masayuki Shibuya πŸ“‚ Article πŸ“… 1992 πŸ› Elsevier Science 🌐 French βš– 272 KB

Synthesis of the sulfone containing lo-membered enediyne derivative 3 and its cycloaromatization in basic conditions via an ailenic sulfone intermediate as well as its DNA cleaving activities are described. The new class of antitumor antibiotics calicheamicins,l esperamicins,\* and dynemicin As hav