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pH Dependence of Specific Divalent Anion Binding to the N-Lobe of Recombinant Human Transferrin

โœ Scribed by Cheng, Yugong; Mason, Anne B.; Woodworth, Robert C.


Book ID
127369735
Publisher
American Chemical Society
Year
1995
Tongue
English
Weight
723 KB
Volume
34
Category
Article
ISSN
0006-2960

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## Abstract Transferrin (TF) is a bilobal transport protein that acquires ferric iron from the diet and holds it tightly within the cleft of each lobe (thereby preventing its hydrolysis). The iron is delivered to actively dividing cells by receptor mediated endocytosis in which diferric TF preferen