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PET study of the distribution of [11C]fluoxetine in a monkey brain

✍ Scribed by Chyng-Yann Shiue; Grace G. Shiue; Kurtis G. Cornish; Maria F. O'Rourke

Book ID
116172017
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
415 KB
Volume
22
Category
Article
ISSN
0969-8051

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By means of positron emission tomography the uptake and kinetics of N-(methyl-11C)clozapine in different brain regions have been studied in Rhesus monkeys. 11C-clozapine rapidly entered the brain and maximum radioactive uptake was seen 5-12 min after administration. Highest uptake was measured in th