Synthesis of radiotracers for studying m
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Robert F. Dannals; Bengt LΓ₯ngstrΓΆm; Hayden T. Ravert; Alan A. Wilson; Henry N. W
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Article
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1988
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Elsevier Science
β 298 KB
Dexetimide (Fig. la), a potent muscarinic cholinergic receptor antagonist, and levetimide (Fig. lb), its pharmacologically inactive enantiomer, were labeled with "C for non-invasive in vivo studies of muscarinic cholinergic receptors in the human brain using positron emission tomography. The synthes