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Perspectives on farnesyl transferase inhibitors in cancer therapy

✍ Scribed by Julien Mazieres; Anne Pradines; Gilles Favre

Book ID
116332888
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
132 KB
Volume
206
Category
Article
ISSN
0304-3835

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The recent interest in inhibitors of farnesyl:protein transferase (FPTase) has resulted in a better understanding of the enzymology of this protein. Rationally designed inhibitors of prenyl transfer have emerged as potential new drug candidates because of the insight gained over how a prenyl group i