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Farnesyl transferase inhibitors: a novel targeted therapy for cancer

✍ Scribed by Stephen RD Johnston

Book ID
117782135
Publisher
The Lancet
Year
2001
Tongue
English
Weight
587 KB
Volume
2
Category
Article
ISSN
1470-2045

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The recent interest in inhibitors of farnesyl:protein transferase (FPTase) has resulted in a better understanding of the enzymology of this protein. Rationally designed inhibitors of prenyl transfer have emerged as potential new drug candidates because of the insight gained over how a prenyl group i