## Abstract Equations for calculation of the initial rates of activated enzymatic reactions and the inhibited enzymatic reactions, unavailable in experimental enzymology, were obtained. Examples of practically using of these equations are given. ยฉ 2009 Wiley Periodicals, Inc. J Biochem Mol Toxicol
Perspectives of data analysis of enzyme inhibition and activation, part 4: Equations for calculation of constants of enzyme activation and inhibition
โ Scribed by Vladimir I. Krupyanko
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 276 KB
- Volume
- 24
- Category
- Article
- ISSN
- 1095-6670
No coin nor oath required. For personal study only.
โฆ Synopsis
Abstract
Equations for calculation of constants of enzyme activation and nontrivial types of enzyme inhibition, which are not reported in the literature, have been deduced. Examples of using these equations are also presented. ยฉ 2010 Wiley Periodicals, Inc. J Biochem Mol Toxicol 24:145โ154, 2010; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/jbt.20316
๐ SIMILAR VOLUMES
## Abstract The possibility of construction of the threeโdimensional (unfolded and folded) __K__~m~โฒ __V__โฒ__I__ rectangular coordinate systems convenient for vector representation of inhibited and activated enzymatic reactions as well as of a twoโdimensional __K__~m~โฒ __V__โฒ scalar rectangular coo
## Abstract A parametrical classification of types of enzymatic reactions that counts 15 typesโ7 inhibited reactions, 7 activated ones, and 1 type of initial (uninhibited and nonactivated) reactionโis considered. The system permits taking into account the number of parameters of enzymatic reactions
This article deals with the effects of the initial concentration of effector (inhibitor or activator) on the steady-state approximation of enzyme kinetics. The results could be summarized as follows: 1) In competitive inhibition, the increase in the initial concentration of inhibitor led to the redu