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Perspectives of data analysis of enzyme inhibition and activation, Part 1: Use of the three-dimensional Km′ V′I coordinate system for data analysis of enzyme inhibition and activation

✍ Scribed by Vladimir I. Krupyanko


Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
111 KB
Volume
23
Category
Article
ISSN
1095-6670

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✦ Synopsis


Abstract

The possibility of construction of the three‐dimensional (unfolded and folded) K~m~′ VI rectangular coordinate systems convenient for vector representation of inhibited and activated enzymatic reactions as well as of a two‐dimensional K~m~′ V′ scalar rectangular coordinate system convenient for diagrammatic representation of enzymatic reactions is considered. The perspectives of using the properties of the three‐dimensional L vectors and their scalar L projections for data analysis of enzyme inhibition and activation are analyzed. © 2009 Wiley Periodicals, Inc. J Biochem Mol Toxicol 23:97–100, 2009; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/jbt.20273


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