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Persistent expression of canine factor IX in hemophilia B canines

โœ Scribed by Chao, H; Samulski, R J; Bellinger, D A; Monahan, P E; Nichols, T C; Walsh, C E


Book ID
110038532
Publisher
Nature Publishing Group
Year
1999
Tongue
English
Weight
216 KB
Volume
6
Category
Article
ISSN
0969-7128

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Heteroduplex analysis in hemophilia B: D
โœ Driscoll, M. Catherine; Chu, Agnes; Hilgartner, Margaret W. ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 256 KB ๐Ÿ‘ 2 views

Heteroduplex analysis of polymerase chain reaction (PCR)-amplified factor IX (FIX) sequences in eight hemophilia B pedigrees localized the causative hemophilia mutation to a single exon in each case. Subsequent PCR-based direct DNA sequence analysis ldentifled two novel FIX mutations and SIX recurre