Heteroduplex analysis of polymerase chain reaction (PCR)-amplified factor IX (FIX) sequences in eight hemophilia B pedigrees localized the causative hemophilia mutation to a single exon in each case. Subsequent PCR-based direct DNA sequence analysis ldentifled two novel FIX mutations and SIX recurre
β¦ LIBER β¦
Regression analysis of amino acid substitutions and factor IX activity in hemophilia B
β Scribed by Makoto Utsunomiya; Makoto Sakamoto; Hiroshi Furutani
- Book ID
- 106246573
- Publisher
- Springer Japan
- Year
- 2009
- Tongue
- English
- Weight
- 438 KB
- Volume
- 13
- Category
- Article
- ISSN
- 1433-5298
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