𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Regression analysis of amino acid substitutions and factor IX activity in hemophilia B

✍ Scribed by Makoto Utsunomiya; Makoto Sakamoto; Hiroshi Furutani


Book ID
106246573
Publisher
Springer Japan
Year
2009
Tongue
English
Weight
438 KB
Volume
13
Category
Article
ISSN
1433-5298

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Heteroduplex analysis in hemophilia B: D
✍ Driscoll, M. Catherine; Chu, Agnes; Hilgartner, Margaret W. πŸ“‚ Article πŸ“… 1996 πŸ› John Wiley and Sons 🌐 English βš– 256 KB πŸ‘ 2 views

Heteroduplex analysis of polymerase chain reaction (PCR)-amplified factor IX (FIX) sequences in eight hemophilia B pedigrees localized the causative hemophilia mutation to a single exon in each case. Subsequent PCR-based direct DNA sequence analysis ldentifled two novel FIX mutations and SIX recurre

Amino acid substitutions in conserved do
✍ Carol Diamond; Scott Kogan; Barbara Levinson; Jane Gitschier πŸ“‚ Article πŸ“… 1992 πŸ› John Wiley and Sons 🌐 English βš– 863 KB

Mutations leading to hemophilia A by substitution of amino acids in coagulation factor VIII may provide important clues to the structure and function of this large and enigmatic protein. To efficiently find missense mutations, hemophiliacs with mild and moderately severe forms of the disease were su