The roles of TNFR1 in lipopolysaccharide
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Hiroki Ochi; Yasushi Hara; Masahiro Tagawa; Kenichi Shinomiya; Yoshinari Asou
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Article
📅
2009
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Elsevier Science
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English
⚖ 753 KB
## Abstract LPS (lipopolysaccharide), a major constituent of Gram‐negative bacteria, regulates proliferation and differentiation of osteoclasts directly or indirectly. This study sought to investigate the functions of the RANK/RANKL pathway in LPS‐induced bone loss in vivo. Wild‐type mice or TNFR1−