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Persistence of mild, early inflammatory arthritis: The importance of disease duration, rheumatoid factor, and the shared epitope

✍ Scribed by Michael Green; Helena Marzo-Ortega; Dennis McGonagle; Richard Wakefield; Susanna Proudman; Philip Conaghan; Jimmy Gooi; Paul Emery


Publisher
John Wiley and Sons
Year
1999
Tongue
English
Weight
159 KB
Volume
42
Category
Article
ISSN
0004-3591

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## Abstract ## Objective To determine whether the HLA–DRB1 shared epitope (SE) is associated with early mortality and specific causes of death in rheumatoid arthritis (RA). ## Methods HLA–DRB1 genotyping was carried out on blood samples from 767 patients recruited for the Early RA Study (ERAS),

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## Abstract ## Objective To study the frequency of allele A of polymorphism PD‐1.3 of the __PDCD1__ gene in patients with rheumatoid arthritis (RA) and its subsets, based on the presence of rheumatoid factor (RF) and the shared epitope (SE) alleles. ## Methods A total of 1,175 patients with RA a