Persistence of HBsAg, HBeAg and Anti-HBe in Healthy Blood Donors
β Scribed by Pentti Ukkonen
- Book ID
- 115108240
- Publisher
- John Wiley and Sons
- Year
- 1980
- Tongue
- English
- Weight
- 279 KB
- Volume
- 38
- Category
- Article
- ISSN
- 0042-9007
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π SIMILAR VOLUMES
Plasma samples from 89 asymptomatic hepatitis B surface antigen (HBsAg) positive volunteer blood donors were titrated for HBsAg by radioimmunoassay using the parallel line method. HBsAg titers ranged widely from 0.01 to 325 pg/ ml. The titers correlated well with hepatitis B viral DNA (HBV DNA) and
A highly sensitive polymerase chain reaction (PCR) was used to analyse serum samples from HBsAg-positive patients in Sweden. Forty-two chronic carriers were tested, five of whom were of Swedish origin. Of the total, there were 13 HBeAg-positive and 27 anti-HBe-positive patients, while 1 patient was
Sera of 17 HBeAg positive and 104 anti-HBe positive asymptomatic HBsAg carriers from two cohorts were tested for HBV DNA. HBV DNA was found in 13 of 17 HBeAg positive carriers (76.5%) and in only 7 of 104 of anti-HBe positive carriers (6.7%). Eleven of the 17 HBeAg positive carriers were retested fo