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Persistence of DNA damage (SCEs) induced by undermethylating agents in CHO cells

✍ Scribed by P. Perticone; R. Cozzi


Book ID
113251605
Publisher
Elsevier Science
Year
1988
Tongue
English
Weight
166 KB
Volume
203
Category
Article
ISSN
0165-1161

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UV-induced sister chromatid exchanges (SCEs) in p53deficient mouse cells were studied to obtain more evidence regarding the involvement of p53 protein in the DNA repair pathway as a checkpoint protein. After 5 J/m2 UV irradiation, mutant-type homozygous cells for p53-deficiency showed the same numbe