Peroxisome proliferator-activated receptor γ 2 mutation may cause a subset of ulcerative colitis
✍ Scribed by Yo Aoyagi; Satoru Nagata; Takahiro Kudo; Toru Fujii; Mariko Wada; Yukihide Chiba; Yoshikazu Ohtsuka; Yuichiro Yamashiro; Toshiaki Shimizu; Toshifumi Ohkusa
- Book ID
- 108973057
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 422 KB
- Volume
- 52
- Category
- Article
- ISSN
- 1328-8067
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Background Peroxisome proliferators-activated receptor γ (PPAR γ ) is a nuclear hormone receptor that serves as a master regulator of adipocytesspecific genes contributing to adipocytes differentiation, susceptibility to obesity, and insulin sensitivity. The substitution of proline to alanine at cod
Peroxisome proliferator-activated receptor gamma (PPARgamma) has been the focus of studies assessing its potential neuroprotective role. These studies have shown either neuroprotection or neurotoxicity by PPARgamma ligands. Comparison of these studies is complicated by the use of different PPARgamma