✦ LIBER ✦

Permeability of phosphatidylcholine and phosphatidylethanolamine bilayers

✍ Scribed by M. Singer

Publisher: Elsevier Science
Year: 1981
Tongue: English
Weight: 767 KB
Volume: 28
Category: Article
ISSN: 0009-3084
DOI: 10.1016/0009-3084(81)90012-8

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✦ Synopsis

Sodium and glucose effluxes were measured in liposomes formed from a series of saturated phosphatidylcholines (PC) and phosphatidylethanolamines (PE). Vesicles composed of a saturated PC display a local permeability maximum in the region of the lipid transition temperature. The height of this maximum is predominantly a function of the thickness of the hydrocarbon chain region. Liposomes formed from a saturated PE do not display such a permeability maximum and in these vesicles the permeability process appears to be controlled by the head group region. It is postulated that the control exerted by the ethanolamine group is due to the reorganization of water structure it induces at the bilayer surface.

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