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Permeability determination and pharmacokinetic study of nobiletin in rat plasma and brain by validated high-performance liquid chromatography method

✍ Scribed by Sheelendra Pratap Singh; Wahajuddin; Divyesh Tewari; Kushalkumar Patel; Girish Kumar Jain


Book ID
113624394
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
644 KB
Volume
82
Category
Article
ISSN
0367-326X

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## Abstract A simple, specific and sensitive HPLC method with UV detection was developed and validated for the determination of tectoridin in rat plasma for the first time. Chromatographic separation was performed on a Welchrom^TM^ C~18~ column (150 Γ— 4.6Β mm, i.d., 5Β Β΅m) at a flow rate of 1.0Β mLΒ mi