Peripheral Blood Mononuclear Cells of the Elderly Contain Varicella-Zoster Virus DNA
โ Scribed by Devlin, M. E.; Gilden, D. H.; Mahalingam, R.; Dueland, A. N.; Cohrs, R.
- Book ID
- 125538362
- Publisher
- University of Chicago Press
- Year
- 1992
- Tongue
- English
- Weight
- 399 KB
- Volume
- 165
- Category
- Article
- ISSN
- 0022-1899
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Varicella zoster-virus (VZV) is a humanpathogenic alpha-Herpesvirus that causes chickenpox after primary infection. The virus spreads by aerosol or direct contact with infectious vesical fluids, it enters the body via the respiratory tract. In a first viremic stage it replicates in local lymph nodes
On the basis of alterations in varicella-zoster virus (VZV) antibody titers, it appears that Bell's palsy in some patients could be associated with VZV reactivation, that is, zoster sine herpete. To obtain stronger evidence of this association, polymerase chain reaction (PCR) was used to detect VZV