Expression of Varicella-Zoster Virus in Blood Mononuclear Cells of Patients with Postherpetic Neuralgia
โ Scribed by Abbas Vafai, Mary Wellish and Donald H. Gilden
- Book ID
- 123635468
- Publisher
- National Academy of Sciences
- Year
- 1988
- Tongue
- English
- Weight
- 934 KB
- Volume
- 85
- Category
- Article
- ISSN
- 0027-8424
- DOI
- 10.2307/31517
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Varicella zoster-virus (VZV) is a humanpathogenic alpha-Herpesvirus that causes chickenpox after primary infection. The virus spreads by aerosol or direct contact with infectious vesical fluids, it enters the body via the respiratory tract. In a first viremic stage it replicates in local lymph nodes
## Abstract The nested polymerase chain reaction was used to detect varicella zoster virus (VZV) DNA in 67 samples of peripheral blood mononuclear cells (PBMC) from 39 otherwise healthy children with varicella. Eleven were during the incubation period and 56 were after appearance of rash. VZV DNA w