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Peripheral B cell abnormalities in patients with systemic lupus erythematosus in quiescent phase: Decreased memory B cells and membrane CD19 expression

✍ Scribed by Anne-Sophie Korganow; Anne-Marie Knapp; Hélène Nehme-Schuster; Pauline Soulas-Sprauel; Vincent Poindron; Jean-Louis Pasquali; Thierry Martin


Book ID
116614273
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
341 KB
Volume
34
Category
Article
ISSN
0896-8411

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## Abstract ## Objective Analysis of peripheral B cell subsets in patients with systemic lupus erythematosus (SLE) has provided evidence of specific alterations, such as an expansion of CD27++ plasma cells/blasts and transitional B cells. However, memory B cells in lupus have not been thoroughly i