Perioperative management of aplastic anemia in pregnancy with platelet transfusion refractoriness
β Scribed by Eiko Onishi; Kazuko Fujita; Satoshi Yokono
- Publisher
- Springer-Verlag
- Year
- 2007
- Tongue
- French
- Weight
- 37 KB
- Volume
- 54
- Category
- Article
- ISSN
- 1496-8975
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The development of alloantibodies to platelets is a major problem in the supportive management of thrombocytopenia in patients with severe aplastic anemia. We report here a case of aplastic anemia refractory to platelet transfusion. An immunosuppressant, cyclosporin A, which was used for the therapy
A %year-old girl with severe refractory aplastic anemia had become refractory to platelet transfusion due to platelet alloimmunization. As a result, a huge right parieto-temporooccipital cerebral hematoma and a subarachnoid hemorrhage subsequently occurred. Intravenous immunoglobulin (IVIG) (Green C
## Abstract In a retrospective study of 126 adult patients with FrenchβAmericanβBritishβdefined refractory anemia with ringed sideroblasts (RARS), staging by the International Prognostic Scoring System was highly predictive of survival outcome (__P__ < 0.0001). In addition, red blood cell (RBC) tra