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Periodic changes in the organs involved in the erythropoiesis of anemic newts

โœ Scribed by Frangioni, Giuliano ;Borgioli, Gianfranco

Publisher
John Wiley and Sons
Year
1987
Tongue
English
Weight
718 KB
Volume
243
Category
Article
ISSN
0022-104X

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โœฆ Synopsis

In Triturus cristatus carnifa aaurenti) newts rendered totally anemic by treatment with acetylphenylhydrazine (APH) diluted in their tank water (25 mgfliter for 48 hours, with four changes) the recovery of erythron occurs through periodic cycles of mitotic activity in the erythropoietic tissue. These cycles determine a marked increase in blood erythrocyte concentration at regular intervals of about 1 month. The consequence of this trend is the alternation of ferritin and hemosiderin accumulation phases during periods of stasis with iron mobilization phases during periods of erythropoietic activity, which is particularly evident in the Kupffer cells of the liver. Iron mobilization and erythropoietic activity are strictly related to the periodic hypertrophy of some Bowman's capsule cells in the renal corpuscle, which

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