Periodate oxidation studies in the elucidation of the structures of sialic acid containing oligosaccharides
β Scribed by W.D. Gathmann; David Aminoff
- Book ID
- 118315342
- Publisher
- Elsevier Science
- Year
- 1981
- Tongue
- English
- Weight
- 290 KB
- Volume
- 100
- Category
- Article
- ISSN
- 0006-291X
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The peeling reaction, the process by which oligosaccharides are degraded in alkali, was used as the basis for an assay to provide structural information about glycosidically linked oligosaccharides in glycoproteins. Glycoproteins were treated with 0.05 M NaOH at 50 degrees to induce release, and sub
The applicability of the reductive-cleavage method to the structural analysis of sialic acid-containing carbohydrates was investigated using fully methylated methyl alpha- and beta-N-acetylneuraminic acid (1 and 2, respectively). Both compounds were fully stable to reductive cleavage in the presence