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Periocular Gene Transfer of Pigment Epithelium-Derived Factor Inhibits Choroidal Neovascularization in a Human-Sized Eye

✍ Scribed by Saishin, Yoshitsugu; Silva, Raquel Lima; Saishin, Yumiko; Kachi, Shu; Aslam, Sadia; Gong, Yuan Yuan; Lai, Hong; Carrion, Miguel; Harris, Brent; Hamilton, Melissa

Book ID: 111916814
Publisher: Mary Ann Liebert
Year: 2005
Tongue: English
Weight: 235 KB
Volume: 16
Category: Article
ISSN: 1043-0342
DOI: 10.1089/hum.2005.16.473

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## Abstract ## Background We previously demonstrated that a new lentiviral vector derived from nonpathogenic simian immunodeficiency virus (SIVagm) was efficient and safe for long‐lasting retinal gene transfer, and that it provided the significant therapeutic effect of expressing human pigment epi