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Perinatal gene delivery to the CNS

โœ Scribed by Rahim, Ahad A; Buckley, Suzanne MK; Chan, Jerry KY; Peebles, Donald M; Waddington, Simon N

Book ID
120891398
Publisher
Future Science
Year
2011
Tongue
English
Weight
819 KB
Volume
2
Category
Article
ISSN
2041-5990

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## Abstract ## Background Direct injection of lentivectors into the central nervous system (CNS) mostly results in localized parenchymal transgene expression. Intrathecal gene delivery into the spinal canal may produce a wider dissemination of the transgene and allow diffusion of secreted transgen