Development of rat pancreatic islet cell
โ
Cheng Kaung, Hue-Lee; Wang, Chen Ya; Chen, Wen-Wha
๐
Article
๐
1998
๐
John Wiley and Sons
๐
English
โ 270 KB
๐ 3 views
Islet cell lines were produced by retroviral transduction of SV-40 T antigen to monolayer cultures of neonatal rat islets. One line, RN0-11, showed evolution of phenotypes in vitro. It evolved from a non-hormone secreting cell line to an insulin secreting line. It further developed glucagon producin