Influence of the neurotoxin capsaicin on rat pancreatic islets in culture, and on the pancreatic islet blood flow of rats
β Scribed by Per-Ola Carlsson; Stellan Sandler; Leif Jansson
- Book ID
- 115891329
- Publisher
- Elsevier Science
- Year
- 1996
- Tongue
- English
- Weight
- 690 KB
- Volume
- 312
- Category
- Article
- ISSN
- 0014-2999
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## Abstract Our objective was to study the effects of three (30, 40, and 50 mg/kg) doses of Streptozotocin (STZ) on fasting plasma glucose level (FPG) and observe its effects at the cellular level in rat pancreas by electron microscopy. FPG was measured in rats before induction of diabetes and then
Blood flow to the pancreatic islets of the rat was estimated with the microsphere technique. Experiments with microspheres of different sizes (diameter 10, 15 or 50 micron) showed that optimal results were obtained with 10-micron spheres. Localization of microspheres either within or outside the isl