Pergolide interactions with nicotine and pilocarpine in rats on the radial-arm maze
β Scribed by EdWard D. Levin
- Book ID
- 113226641
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- English
- Weight
- 471 KB
- Volume
- 52
- Category
- Article
- ISSN
- 0091-3057
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π SIMILAR VOLUMES
I n rats, the effects of an intracerebroventricular (ICV) nicotinic agonist nicotine (NIC), the nicotinic antagonist mecamylamine (MEC), and combinations of NIC + MEC were assessed in a radial-arm maze (RAM). In experiment 1, exploratory behavior was assessed in untrained rats (N = 13). The rats rec
Nicotine and other nicotinic agonists have been found to improve performance in a variety of tasks, including the radial-arm maze to improve memory. There has been an active effort to develop novel nicotinic agonists for the treatment of cognitive dysfunction such as is seen in Alzheimer's disease.