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Percutaneous absorption of alkanoic acids I: A study of operational conditions

✍ Scribed by Zvi Liron; Sasson Cohen


Publisher
John Wiley and Sons
Year
1984
Tongue
English
Weight
501 KB
Volume
73
Category
Article
ISSN
0022-3549

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πŸ“œ SIMILAR VOLUMES


Percutaneous absorption of alkanoic acid
✍ Zvi Liron; Sasson Cohen πŸ“‚ Article πŸ“… 1984 πŸ› John Wiley and Sons 🌐 English βš– 549 KB

The permeability coefficient, K p , of pure unbranched alkanoic acids (Cz-C,) applied to isolated porcine skin, reached a maximum in the solubility parameter ( 8 2 ) range of 9.7-10 ~a l ' / ~/ c m ~/ ~. When these and other penetrants were delivered from a solvent vehicle, the following linear rel

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Several theoreticals for simulating percutaneous drug absorption with a computer aid are proposed. By using our theoreticals, the simulation can be made for the process not only during an ointment application but also after its removal. The tlow rate of drug from vehicle to skin and that from skin t

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✍ A. S. Susten; B. L. Dames; R. W. Niemeier πŸ“‚ Article πŸ“… 1986 πŸ› John Wiley and Sons 🌐 English βš– 444 KB

A stainless-steel skin-depot is discussed that may be used during short-term studies to measure directly percutaneous absorption of radiolabeled, volatile chemicals through the skin of unanesthetized, unrestrained hairless mice. The skin-depot is glued to the backs of the mice using cyanoacrylate gl