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Percutaneous absorption, disposition, and excretion of 4,4′-methylenebis(2-chloroaniline) in dogs

✍ Scribed by Melanie O. Manis; Daniel E. Williams; Kevin M. McCormack; Robert J. Schock; Lisa F. Lepper; Yuk-Chow Ng; W.Emmett Braselton


Book ID
115873992
Publisher
Elsevier Science
Year
1984
Tongue
English
Weight
798 KB
Volume
33
Category
Article
ISSN
0013-9351

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Percutaneous absorption and disposition
✍ Fikrat W. Ezzedeen; Sidney J. Stohs; Karen L. Kilzer; Michael C. Makoid; Nihad W 📂 Article 📅 1984 🏛 John Wiley and Sons 🌐 English ⚖ 464 KB

The percutaneous absorption and disposition of iodochlorhydroxyquin (5-chloro-7-iodo-8-quinolinol; I) from a 3% cream were studied in five dogs over a 28-d topical treatment period. Plasma levels, determined by HPLC, were 0.275-0.525 microgram/mL. The steady-state elimination rate of total I in urin