Peptoid–Peptide Hybrid Backbone Architectures
✍ Scribed by Christian A. Olsen
- Book ID
- 102791286
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 551 KB
- Volume
- 11
- Category
- Article
- ISSN
- 1439-4227
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## Abstract Nano‐electrospray tandem mass spectrometry (nano‐ES‐MS/MS) was used to record collision‐induced dissociation (CID) spectra of a set of peptoid–peptide hybrids and the complete peptoid derived from the phosphopeptide Ac‐pTyr‐Glu‐Thr‐Leu‐NH~2~ (1). The presence of B and Y″‐type fragment i
## Abstract A series of peptide–peptoid hybrids, containing __N__‐substituted glycines, were synthesized based on the H‐Aib‐Val‐Aib‐Glu‐Ile‐Gln‐Leu‐Nle‐His‐Gln‐Har‐NH~2~ (Har = Homoarginine) as the parent parathyroid hormone (1–11) analog. The compounds were pharmacologically characterized in their