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Peptidylarginine deiminase type 4, anticitrullinated peptide antibodies, and rheumatoid arthritis

✍ Scribed by Ryo Yamada

Book ID: 113481675
Publisher: Elsevier Science
Year: 2005
Tongue: English
Weight: 294 KB
Volume: 4
Category: Article
ISSN: 1568-9972
DOI: 10.1016/j.autrev.2004.11.002

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## Abstract ## Objective Protein citrullination is an important posttranslational modification recognized by rheumatoid arthritis (RA)–specific autoantibodies. One of the citrullinating enzymes, peptidyl arginine deiminase type 4 (PAD‐4), is genetically associated with development of RA in some po