✦ LIBER ✦

Peptidic modulators of protein-protein interactions: Progress and challenges in computational design

✍ Scribed by Mor Rubinstein; Masha Y. Niv

Publisher: Wiley (John Wiley & Sons)
Year: 2009
Tongue: English
Weight: 161 KB
Volume: 91
Category: Article
ISSN: 0006-3525
DOI: 10.1002/bip.21164

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Peptidic modulators of protein-protein i

Peptidic modulators of protein-protein interactions: Progress and challenges in computational design

✍ Mor Rubinstein; Masha Y. Niv 📂 Article 📅 2009 🏛 Wiley (John Wiley & Sons) 🌐 English ⚖ 161 KB 👁 1 views

## Abstract With the decline in productivity of drug‐development efforts, novel approaches to rational drug design are being introduced and developed. Naturally occurring and synthetic peptides are emerging as novel promising compounds that can specifically and efficiently modulate signaling pathwa

Computational challenges in combinatoria

Computational challenges in combinatorial library design for protein engineering

✍ Gregory L. Moore; Costas D. Maranas 📂 Article 📅 2004 🏛 American Institute of Chemical Engineers 🌐 English ⚖ 231 KB 👁 2 views

ChemInform Abstract: Design of Peptides,

ChemInform Abstract: Design of Peptides, Proteins, and Peptidomimetics in Chi Space

✍ V. J. HRUBY; G. LI; C. HASKELL-LUEVANO; M. SHENDEROVICH 📂 Article 📅 2010 🏛 John Wiley and Sons ⚖ 24 KB

The Impact of Amino Acid Side Chain Muta

The Impact of Amino Acid Side Chain Mutations in Conformational Design of Peptides and Proteins

✍ Burkhardt Laufer; Andreas O. Frank; Jayanta Chatterjee; Thomas Neubauer; Carles 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 442 KB 👁 1 views

Direct computation of long time processe

Direct computation of long time processes in peptides and proteins: Reaction path study of the coil-to-helix transition in polyalanine

✍ Shuanghong Huo; John E. Straub 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 414 KB 👁 1 views

The MaxFlux reaction path algorithm was used to isolate optimal transition pathways for the coil-to-helix transition in polyalanine. Eighteen transition pathways, each connecting one random coil configuration with an ideal ␣-helical configuration, were computed and analyzed. The transition pathway e

Expression and phosphorylation of a MARC

Expression and phosphorylation of a MARCKS-like protein in gastric chief cells: Further evidence for modulation of pepsinogen secretion by interaction of Ca2+/calmodulin with protein kinase C

✍ Jean-Pierre Raufman; Ravindra Malhotra; Qian Xie; Robert D. Raffaniello 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 228 KB 👁 2 views

In gastric chief cells, agents that activate protein kinase C (PKC) stimulate pepsinogen secretion and phosphorylation of an acidic 72-kDa protein. The isoelectric point and molecular mass of this protein are similar to those for a common PKC substrate; the MARCKS (for Myristoylated Alanine-Rich C K