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Computational challenges in combinatorial library design for protein engineering

โœ Scribed by Gregory L. Moore; Costas D. Maranas


Publisher
American Institute of Chemical Engineers
Year
2004
Tongue
English
Weight
231 KB
Volume
50
Category
Article
ISSN
0001-1541

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One common synthetic route creates small-molecule libraries directed toward two functionally distinct target families. The novel structural template 1 can independently display the necessary pharmacophore patterns for inhibition of members of two different biomolecular target families, the matrix me