Peptides: the cornerstone of HLA-B27 biology and pathogenetic role in spondyloarthritis
✍ Scribed by M. Marcilla; J. A. López de Castro
- Book ID
- 110892781
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 267 KB
- Volume
- 71
- Category
- Article
- ISSN
- 0001-2815
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📜 SIMILAR VOLUMES
Population and peptide specificity analyses and studies in transgenic rodents support a role of HLA-B27 as an antigen-presenting molecule in spondyloarthropathy. The interplay between HLA-B27 and arthritogenic bacteria on infected cells suggests that HLA-B27 might also influence disease by other mec
Previous studies indicated the increase of HLA-B39 among HLA-B27 negative patients with spondylarthropathies (SpA). This study was performed to examine whether the natural ligands of HLA-B27 are capable of binding to HLA-B39. Methods. Peptides were synthesized according to the sequences of known nat